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Lindane - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Note: See Working with the Information on this Page section below for important notes about this data.

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Chemical ID
 Identifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of all products containing this chemical and a list of the top crops this pesticide is used on in California.
Poisoning Symptoms
 Signs and symptoms of poisoning, first aid, and links to treatment information for this chemical.
Toxicity
 Link to information on toxicity to humans, including carcinogenicity, reproductive and developmental toxicity, neurotoxicity, and acute toxicity.
Regulatory
 Links to world-wide registration status as well as regulatory information for the U.S. and California.
Water
 Water quality standards and physical properties affecting water contamination potential.
Ecotoxicity
 Toxicity to aquatic organisms.
Related Chems
 List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.
 

Chemical Identification and Use for Lindane
Basic Identification Information About This Chemical
Chemical Name: Lindane
CAS Number: 58-89-9
U.S. EPA PC Code: 009001
CA DPR Chem Code: 359
Molecular Weight: 290.83
Molecular Structure:
Use Type: Drug , Insecticide , Rodenticide
Chem Class: Organochlorine
View Related Chemicals
 
Additional Resources About This Chemical Class and Use Type
 
Other Names for this Chemical
About Chemical Synonyms
(US EPA PC Code ) , (1alpha,2alpha,3beta,4alpha,5alpha,6beta)-1,2,3,4,5,6-Hexachlorocyclohexane , 009001 (US EPA PC Code Text ) , 050 (PDP Code) , 359 (CA DPR Chem Code) ) , 58-89-9 (CAS number) , 58899 , 58899 (CAS number without hyphens) , Benhexachlor , BHC, gamma isomer , Exagama , Forlin , Gallouama , Gamaphex , Gamma isomer of benzene hexachloride from lindane , Gamma-1,2,3,4,5,6-hexachlorocyclohexane , gamma-BHC , Gamma-BHC from lindane , Gamma-HCH , Gamma-HCH , Lindane , gamma-Hexachlorocyclohexane , gamma-Hexachlorocyclohexane(HCH or Lindane) , Gammex , Hexachlorocyclohexane (gamma isomer) , Hexachlorocyclohexane, gamma- , Inexit , Isotox , Lindafor , Lindagam , Lindagrain , Lindagranox , Lindalo , Lindamul , Lindan , Lindane , Lindane ( Gamma isomer of benzene hexachloride ) (99% pure gamma isomer required) , Lindane (BHC gamma) , LINDANE (CA DPR Chem Code Text ) , Lindane (gamma - HCH) , lindane (gamma-bhc) , Lindane (gamma-HCH) , Lindane and other hexachlorocyclohexane isomers , Lindane [Cyclohexane, 1,2,3,4,5,6-hexachloro-,(1.alpha.,2.alpha.,3.beta.,4.alpha.,5.alpha.,6.beta.)-] , Lindano , Lindapoudre , Lindaterra , Novigan , OMS 17 , Silvanol , ? -Hexachlorocyclohexane (under Lindane and Other Hexachlorocyclohexane
 
Products Containing This Chemical
Current and historic U.S. registered products
View U.S. Products All Products Currently Registered Products
 

Signs and Symptoms of Lindane Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.

Lindane is a Organochlorine compound.

Report a Poisoning
Symptoms of Poisoning with Organochlorine Compounds
Find Products Containing this Chemical

- Hypersensitive to stimulation, sensation of prickling, tingling or creeping on skin.
- Headache, dizziness, nausea, vomiting, incoordination, tremor, mental confusion, hyperexcitable state.
- In severe cases: convulsions, seizures, coma and respiratory depression.

Source for Group Symptoms: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 6.
Treatment for Organochlorine Poisoning

See: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 6, page 58.

 
Symptoms of Lindane Exposure from the International Chemical Safety Cards (ICSC)

Report a Poisoning
View full ICSC Cards: English   Español   Française   Chinese   Dutch   Finnish   German   Hungarian   Japanese   Swahili   Thai   Urdu  
NOTE! PREVENT DISPERSION OF DUST! STRICT HYGIENE!

Route of Exposure

Symptoms

First Aid
Inhalation Convulsions. Cough. Dizziness. Headache. Nausea. Weakness. Tremors. Paresthesias. Symptoms may be delayed (see Notes). Fresh air rest. Artificial respiration if indicated. Refer for medical attention.
Skin MAY BE ABSORBED! Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention. Wear protective gloves when administering first aid.
Eyes Redness. First rinse with plenty of water for several minutes (remove contact lenses if easily possible) then take to a doctor.
Ingestion Abdominal pain. Diarrhoea. (Further see Inhalation). Rinse mouth. Give a slurry of activated charcoal in water to drink. Do NOT induce vomiting. Give plenty of water to drink. Rest. Refer for medical attention.
Notes for ICSC Information
Depending on the degree of exposure periodic medical examination is indicated. Carrier solvents used in commercial formulations may change physical and toxicological properties. The relation between odour and the occupational exposure limit cannot be indicated. Do NOT take working clothes home. Gammexane Tri-6 Lindafor Lindatox Agrocide Isotox Esoderm Aparasin are trade names.
 

Toxicity Information for Lindane

  Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

Summary Toxicity Information

PAN Bad Actor
Chemical 1 		Acute
Toxicity 2 		Carcinogen Cholinesterase
Inhibitor 		Ground
Water Contaminant 		Developmental or
Reproductive Toxin 		Endocrine
Disruptor
No
Suspected
 
Indicates high toxicity in the given toxicological category. Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Detailed Toxicity Information
Acute Toxicity 2
 Lindane
WHO Acute Hazard
TRI Acute Hazard
Material Safety Data Sheets
Acute rating from U.S. EPA product label
U.S. NTP Acute Toxicity Studies
      View Studies
Cholinesterase Inhibitor		 II, Moderately Hazardous
Not Listed
Not Available
Moderately Toxic
Moderately to Highly Toxic

No
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.
 
Cancer Information
 Lindane
IARC Carcinogens
U.S. NTP Carcinogens
California Prop 65 Known Carcinogens
U.S. EPA Carcinogens
TRI Carcinogen		 2B, Possible
Reasonably Anticipated
Yes
Suggestive
Not Listed
 
Endocrine Disruption
 Lindane
Illinois EPA list
Keith list
Colborn list
Benbrook list
Danish Inert list
EU list		 Known
Yes
Yes
Yes
Not listed
Yes
 
Reproductive and Developmental Toxicity
 Lindane
CA Prop 65 Developmental Toxin
U.S. TRI Developmental Toxin
CA Prop 65 Female Reproductive Toxin
CA Prop 65 Male Reproductive Toxin
U.S. TRI Reproductive Toxin 		Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 
Chemicals of Special Concern
 Lindane
PAN Bad Actors
PAN Dirty Dozen list		 Yes
Yes
 

Water Pollution Potential and Criteria for Lindane

Water Pollution Potential

PAN Ground Water Contaminant Rating Insufficient Data
 
Physical Property Data Related to Water Contamination Potential
Water Solubility (Avg, mg/L)
Adsorption Coefficient (Koc)
Hydrolysis Half-life (Avg, Days)
Aerobic Soil Half-life (Avg, Days)
Anaerobic Soil Half-life (Avg, Days) 		8.52
1,100
467.0
121.0
- 		 
 

Water Standards and Criteria
U.S. National Drinking Water Standards and Health Criteria
 µg/L unless noted  
Maximum Contaminant Level (MCL) 0.20  
Maximum Contaminant Level Goal (MCLG) 0.20  
One Day Exposure Health Advisory Level 1,000  
Ten Day Exposure Health Advisory Level 1,000  
Lifetime Exposure Health Advisory Level  
Reference Dose 5.00 (µg/kg/day)  
U.S. Drinking Water Equivalent Level 200.0  
Concentration with Lifetime Cancer Risk of 1 in 10,000  
U.S. National Water Quality Criteria
 µg/L unless noted  
Fresh Water Quality Criteria Continuous Exposure  
Fresh Water Quality Criteria Maximum Peak 0.95 Notes: k  
Salt Water Quality Criteria Continuous Exposure
Salt Water Quality Criteria Max 0.16 Notes: g
Human Consumption of Organisms from Water Source 1.80
Human Consumption of Water and Organisms from Water Source 0.98
Taste and Odor Criteria
WHO Water Quality Criteria
Concentration (μg/l unless otherwise noted) 2.0
 

Regulatory Information for Lindane

International Regulatory Status
 
UNEP Persistent Organic Pollutant (POP)
UNEP Prior Informed Consent Chemical (PIC)
WHO Obsolete Pesticide		 Reviewed
Yes
Not Listed
 

U.S. and California Regulatory Status
U.S. EPA Registered
U.S. EPA Hazardous Air Pollutant
U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered
CA Groundwater Contaminant
CA Toxic Air Contaminant 		No
Yes
No

No
Not Listed
HAPTAC, Pesti
 

Maximum Tolerance and Residue Levels
Codex Alimentarius
   (UN FAO Maximum Residue Limits)
U.S. Maximum Tolerance Levels
European Union Maximum Residue Levels 		Go to web site

Go to web site
Go to web site
 

Ecotoxicity for Lindane

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.

Aquatic Ecotoxicity
All Toxic Effects for Organism Group
Organism Group Effects Noted
Amphibians Accumulation, Behavior, Cell(s), Development, Growth, Histology, Morphology, Mortality, Physiology
Annelida Accumulation, Development, Intoxication, Mortality
AquaticPlants Accumulation, Biochemistry, Enzyme(s), Growth, Physiology, Population
Cnidaria Growth, Histology, Population
Crustaceans Accumulation, Behavior, Biochemistry, Development, Genetics, Growth, Hormone(s), Mortality, No Effect Coded, Physiology, Population, Reproduction
Echinoderms Behavior
Fish Accumulation, Avoidance, Behavior, Biochemistry, Cell(s), Development, Enzyme(s), Feeding Behavior, Genetics, Growth, Histology, Hormone(s), Immunological, Intoxication, Morphology, Mortality, No Effect Coded, Physiology, Reproduction
Insects Accumulation, Behavior, Development, Enzyme(s), Genetics, Growth, Histology, Intoxication, Mortality, Physiology, Population, Reproduction
Molluscs Accumulation, Behavior, Biochemistry, Development, Enzyme(s), Feeding Behavior, Growth, Intoxication, Morphology, Mortality, Physiology, Reproduction
NematodesandFlatworms Development, Intoxication, Mortality, Population, Reproduction
Phytoplankton Accumulation, Behavior, Biochemistry, Cell(s), Development, Ecosystem Process, Genetics, Growth, Histology, Mortality, Physiology, Population, Reproduction
Zooplankton Accumulation, Behavior, Biochemistry, Development, Enzyme(s), Feeding Behavior, Growth, Histology, Intoxication, Morphology, Mortality, No Effect Coded, Physiology, Population, Reproduction
~ Un-Assigned Accumulation, Biochemistry, Mortality, Population
View All Aquatic Ecotoxicity Studies and References
 
Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
Amphibians Moderately Toxic Moderate to High Toxicity
Annelida Moderately Toxic Slight to Moderate Toxicity
Crustaceans Moderately Toxic Slight to Very High Toxicity
Fish Highly Toxic Slight to Very High Toxicity
Insects Very Highly Toxic High to Very High Toxicity
Molluscs Moderately Toxic Slight to High Toxicity
NematodesandFlatworms Moderately Toxic Moderate to High Toxicity
Zooplankton Moderately Toxic Slight to Very High Toxicity
~ Un-Assigned Moderately Toxic Moderate to Very High Toxicity
View All Acute Summaries
 

Terrestrial Ecotoxicity
Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
HoneybeesHighly ToxicHighly Toxic
Note: Population-level effects on honeybees may occur even if a pesticide has low acute toxicity. For example, certain pesticides interfere with honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.
Honeybee Chronic Toxicity

Sorry, no honeybee chronic toxicity data available for this chemical. Try related chemicals.

Related Chemicals for Lindane
CAS Number Relation Reason Chemical Name Chem Detail Symptoms California Use Chem Use Type U.S. EPA Reg PAN Bad Actor
58-89-9 Parent P Lindane View View View Insecticide, Rodenticide No Yes
319-84-6 Related 6 alpha-HCH View View View Insecticide No Yes
319-85-7 Related 6 beta-HCH View View View Insecticide No Yes
Related 6 BHC (other than gamma isomer) View View View Insecticide No Yes
Related 6 BHC delta View View View Insecticide No Yes
608-73-1, 319-86-8 Related 13 Hexachlorocyclohexane View View View Insecticide No Yes
 
Working with the Information on this Page

Click on underlined terms for definitions or go to the Pesticide Tutorial overview page.

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* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

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Citation: Kegley, S.E., Hill, B.R., Orme S., Choi A.H., PAN Pesticide Database, Pesticide Action Network, North America (Oakland, CA, 2014), http:www.pesticideinfo.org.
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