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Dioxin (2,3,7,8-TCDD) - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Note: See Working with the Information on this Page section below for important notes about this data.

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Chemical ID
 Identifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of all products containing this chemical and a list of the top crops this pesticide is used on in California.
Poisoning Symptoms
 Signs and symptoms of poisoning, first aid, and links to treatment information for this chemical.
Toxicity
 Link to information on toxicity to humans, including carcinogenicity, reproductive and developmental toxicity, neurotoxicity, and acute toxicity.
Regulatory
 Links to world-wide registration status as well as regulatory information for the U.S. and California.
Water
 Water quality standards and physical properties affecting water contamination potential.
Ecotoxicity
 Toxicity to aquatic organisms.
Related Chems
 List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.
 

Chemical Identification and Use for Dioxin (2,3,7,8-TCDD)
Basic Identification Information About This Chemical
Chemical Name: Dioxin (2,3,7,8-TCDD)
CAS Number: 1746-01-6
U.S. EPA PC Code: 600000 (US EPA PC Code for this chemical as an impurity)
CA DPR Chem Code: 4068
Molecular Weight: 321.96
Molecular Structure:
Use Type: Impurity
Chem Class: Organochlorine
View Related Chemicals
 
Additional Resources About This Chemical Class and Use Type

See the Global Pesticide Resources page for many additional links.
 
Other Names for this Chemical
About Chemical Synonyms
04068 (CA DPR Chem Code Text) , 04068 (CA DPR Chem Code) , 1746-01-6 (CAS number) , 1746016 , 1746016 (CAS number without hyphens) , 2,3,7,8-TCDD (as impurity or contaminant) , 2,3,7,8-TCDD Dioxin , 2,3,7,8-Tetrachlorodibenzo-1,4-dioxin , 2,3,7,8-Tetrachlorodibenzo-p -dioxin (TCDD) , 2,3,7,8-Tetrachlorodibenzo-p-dioxin , 2,3,7,8-tetraclorodibenzo-p-dioxin , 4068 (CA DPR Chem Code) , 4068 (CA DPR Chem Code) , 600000 (US EPA PC Code Text) , 600000 (US EPA PC Code) , Chlorinated Dibenzo-p-dioxins , Chlorinated Dibenzo-p-Dioxins(CDDs) , Dibenzo(b,e)(1,4)dioxin, 2,3,7,8-tetrachloro- , Dibenzo-p-dioxin, 2,3,7,8-tetrachloro- , Dibenzo-p-dioxin, 2,3,7,8-tetrachloro- (6CI, 7CI, 8CI) , Dioxin , Dioxin (2,3,7,8-TCDD) , Dioxin (as impurity or contaminant) , Dioxin2378TCDD , Dioxins , Dioxins (CDDs) , Polychlorinated dibenzo-p-dioxins , TCDBD , TCDD
 
Products Containing This Chemical
Current and historic U.S. registered products
View U.S. Products All Products Currently Registered Products
 

Signs and Symptoms of Dioxin (2,3,7,8-TCDD) Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.

Symptoms of Dioxin (2,3,7,8-TCDD) Exposure from the International Chemical Safety Cards (ICSC)

Report a Poisoning
View full ICSC Cards: English   Español   Française   Chinese   Dutch   Finnish   German   Hungarian   Japanese   Swahili   Thai   Urdu  
NOTE! AVOID ALL CONTACT!
 General First Aid: IN ALL CASES CONSULT A DOCTOR!

Route of Exposure

Symptoms

First Aid
Inhalation Chloracne. Symptoms may be delayed. Fresh air rest. Refer for medical attention.
Skin MAY BE ABSORBED! Redness. Pain. (See Inhalation). Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
Eyes Redness. Pain. First rinse with plenty of water for several minutes (remove contact lenses if easily possible) then take to a doctor.
Ingestion (See Inhalation). Give a slurry of activated charcoal in water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Notes for ICSC Information
This chemical is only produced for research purposes but could be generated as a by-product from chemical processes or fires.
 

Toxicity Information for Dioxin (2,3,7,8-TCDD)

  Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

Summary Toxicity Information

PAN Bad Actor
Chemical 1 		Acute
Toxicity 2 		Carcinogen Cholinesterase
Inhibitor 		Ground
Water Contaminant 		Developmental or
Reproductive Toxin 		Endocrine
Disruptor
No
Suspected
 
Indicates high toxicity in the given toxicological category. Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Additional Resources about the Toxicity of this Chemical

See the Global Pesticide Resources page for many additional links.

Detailed Toxicity Information
Acute Toxicity 2
 Dioxin (2,3,7,8-TCDD)
WHO Acute Hazard
TRI Acute Hazard
Material Safety Data Sheets
Acute rating from U.S. EPA product label
U.S. NTP Acute Toxicity Studies
      View Studies
Cholinesterase Inhibitor		 Not Listed
Not Listed
Not Available
No Consensus Value
Highly Toxic

No
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.
 
Cancer Information
 Dioxin (2,3,7,8-TCDD)
IARC Carcinogens
U.S. NTP Carcinogens
California Prop 65 Known Carcinogens
U.S. EPA Carcinogens
TRI Carcinogen		 1, Known
Known
Yes
Not Listed
Not Listed
 
Endocrine Disruption
 Dioxin (2,3,7,8-TCDD)
Illinois EPA list
Keith list
Colborn list
Benbrook list
Danish Inert list
EU list		 Not Listed
Yes
Yes
Not Listed
Not listed
Yes
 
Reproductive and Developmental Toxicity
 Dioxin (2,3,7,8-TCDD)
CA Prop 65 Developmental Toxin
U.S. TRI Developmental Toxin
CA Prop 65 Female Reproductive Toxin
CA Prop 65 Male Reproductive Toxin
U.S. TRI Reproductive Toxin 		Yes
Not Listed
Not Listed
Not Listed
Not Listed
 
Chemicals of Special Concern
 Dioxin (2,3,7,8-TCDD)
PAN Bad Actors
PAN Dirty Dozen list		 Yes
 

Water Pollution Potential and Criteria for Dioxin (2,3,7,8-TCDD)

Water Pollution Potential

PAN Ground Water Contaminant Rating Insufficient Data
 

Water Standards and Criteria
U.S. National Drinking Water Standards and Health Criteria
 µg/L unless noted  
Maximum Contaminant Level (MCL) 0.0000  
Maximum Contaminant Level Goal (MCLG) 0  
One Day Exposure Health Advisory Level 0.0010  
Ten Day Exposure Health Advisory Level 0.0001  
Lifetime Exposure Health Advisory Level  
Reference Dose 0.0000 (µg/kg/day)  
U.S. Drinking Water Equivalent Level 0.0000  
Concentration with Lifetime Cancer Risk of 1 in 10,000 0.0000  
U.S. National Water Quality Criteria
 µg/L unless noted  
Fresh Water Quality Criteria Continuous Exposure  
Fresh Water Quality Criteria Maximum Peak  
Salt Water Quality Criteria Continuous Exposure
Salt Water Quality Criteria Max
Human Consumption of Organisms from Water Source 0.0000 Notes: c
Human Consumption of Water and Organisms from Water Source 0.0000 Notes: c
Taste and Odor Criteria
 

Regulatory Information for Dioxin (2,3,7,8-TCDD)

International Regulatory Status
Registration in Selected Countries Registration in Selected Countries:
Dioxin (2,3,7,8-TCDD)
 
UNEP Persistent Organic Pollutant (POP)
UNEP Prior Informed Consent Chemical (PIC)
WHO Obsolete Pesticide		 Yes

Not Listed
 

U.S. and California Regulatory Status
U.S. EPA Registered
U.S. EPA Hazardous Air Pollutant
U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered
CA Groundwater Contaminant
CA Toxic Air Contaminant 		No
Yes
No

No
Not Listed
HAPTAC, Indus
 

Maximum Tolerance and Residue Levels
Codex Alimentarius
   (UN FAO Maximum Residue Limits)
U.S. Maximum Tolerance Levels
European Union Maximum Residue Levels 		Go to web site

Go to web site
Go to web site
 

Ecotoxicity for Dioxin (2,3,7,8-TCDD)

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.

Aquatic Ecotoxicity
All Toxic Effects for Organism Group
Organism Group Effects Noted
Amphibians Accumulation, Behavior, Development, Growth, Mortality, Physiology
Annelida Accumulation, Population
AquaticPlants Accumulation
Crustaceans Accumulation, Enzyme(s), Histology, Mortality
Fish Accumulation, Biochemistry, Cell(s), Development, Enzyme(s), Feeding Behavior, Genetics, Growth, Histology, Hormone(s), Injury, Intoxication, Morphology, Mortality, Physiology, Population, Reproduction
Insects Accumulation, Development, Growth, Mortality, Physiology, Population, Reproduction
Molluscs Accumulation, Reproduction
Phytoplankton Accumulation, Behavior
Zooplankton Accumulation, Mortality, Reproduction
View All Aquatic Ecotoxicity Studies and References
 
Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
Fish Moderately Toxic Moderate Toxicity
View All Acute Summaries
 

Terrestrial Ecotoxicity

We are seeking funding to incorporate terrestrial ecotoxicity data analogous to the aquatic ecotoxicity data in the space above. Watch this space!

Related Chemicals for Dioxin (2,3,7,8-TCDD)
CAS Number Relation Reason Chemical Name Chem Detail Registration Symptoms California Use Chem Use Type U.S. EPA Reg PAN Bad Actor
1746-01-6 Parent P Dioxin (2,3,7,8-TCDD) View View View View Impurity No Yes
Related 2 Dibenzo-para-dioxin View View View View Impurity No Not Listed
Related 2 Dioxin (other than 2,3,7,8-TCDD) View View View View Impurity No Not Listed
34465-46-8 Related 2 Hexachloro dibenzo-p-dioxin View View View View Impurity No Yes
 
Working with the Information on this Page

Click on underlined terms for definitions or go to the Pesticide Tutorial overview page.

Any underlined term with a book icon has additional information.

* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

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Citation: Kegley, S.E., Hill, B.R., Orme S., Choi A.H., PAN Pesticide Database, Pesticide Action Network, North America (San Francisco, CA, 2010), http:www.pesticideinfo.org.
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