PAN Pesticides Database - Chemicals

MCPA - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Note: See Working with the Information on this Page section below for important notes about this data.

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Identifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of all products containing this chemical and a list of the top crops this pesticide is used on in California.
Signs and symptoms of poisoning, first aid, and links to treatment information for this chemical.
Link to information on toxicity to humans, including carcinogenicity, reproductive and developmental toxicity, neurotoxicity, and acute toxicity.
Links to world-wide registration status as well as regulatory information for the U.S. and California.
Water quality standards and physical properties affecting water contamination potential.
Toxicity to aquatic organisms.
List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.
 

Chemical Identification and Use for MCPA

Basic Identification Information About This Chemical
Chemical Name: MCPA
CAS Number: 94-74-6
U.S. EPA PC Code: 030501
030501
CA DPR Chem Code: 2326
Molecular Weight: 200.6
Use Type: Herbicide
Chem Class: Chlorophenoxy acid, salt, or ester
View Related Chemicals
 
Additional Resources About This Chemical Class and Use Type
 
Other Names for this Chemical
About Chemical Synonyms
(4-Chloro-o-cresoxy)acetic acid , (4-Chloro-o-tolyloxy)acetic acid , 02326 (CA DPR Chem Code Text ) , 030501 [US EPA PC Code, Text ] , 2,4-MCPA , 2-(4-chloro-2-methylphenoxy)acetic acid , 2-Methyl-4-chlorophenoxyacetic acid , 2326 (CA DPR Chem Code) ) , 30501 [US EPA PC Code, Numeric ] , 318 (PDP Code) , 4-Chloro-2-methylphenoxyacetic acid , 4-chloro-o-tolyloxyacetic acid , 94-74-6 (CAS number) , 94746 , 94746 (CAS number without hyphens) , Acetic acid, ((4-chloro-o-tolyl)oxy)- , Acetic acid, (4-chloro-2-methylphenoxy)- , Acetic acid, 2-methyl-4-chlorophenoxy- , Agroxone , Anicon kombi , Anicon M , B-Selektonon M , BAS 009H , BH MCPA , Bordermaster , Cekherbex , Chiptox , Chwastox , CMP Acetate , Cornox-M , Ded-Weed , Dicopur-M , Dikotex , Emcepan , Empal , Hedapur M 52 , Hedarex M , Hedonal , Hedonal M , Herbicide M , Hormotuho , Kilsem , Krezone , Leuna M , Linormone , M 40 , M.C.P.A. , MCPA , MCPA (and salts and esters) , MCPA (PRESENT AS ACID) , MCPA present as acid , MCPA, ACID , Mephanac , Metaxon , Methoxone ((4-Chloro-2-methylphenoxy)acetic acid) (MCPA) , Methyl Chlorophenoxy Acetic Acid (MCPA) , Phenoxylene Plus , Rhomene , Rhonox , Shamrox , U 46 M-Fluid 4 , Vacate , Weed-Rhap , Weedar , Weedone , Zelan
 
Products Containing This Chemical
Current and historic U.S. registered products
View U.S. Products All Products Currently Registered Products
 

Signs and Symptoms of MCPA Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.

MCPA is a Chlorophenoxy compound.

Report a Poisoning

Symptoms of Poisoning with Chlorophenoxy Compounds
Find Products Containing this Chemical

- Irritation of skin, eyes and respiratory tract.
- Inhalation may cause burning sensation in nasopharynx and chest, coughing, and/or dizziness.
- Headache, vomiting, diarrhea.
- Confusion, bizarre or aggressive behavior.
- Kidney failure, increased heart rate.
- Metabolic acidosis resulting in peculiar odor on breath.

Source for Group Symptoms: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 9.

Treatment for Chlorophenoxy Poisoning

See: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 9, page 96.

 
Symptoms of MCPA Exposure from the International Chemical Safety Cards (ICSC)

Report a Poisoning

View full ICSC Cards: English   Español   Française   Chinese   Dutch   Finnish   German   Hungarian   Japanese   Swahili   Thai   Urdu  
NOTE! PREVENT DISPERSION OF DUST! AVOID EXPOSURE OF (PREGNANT) WOMEN!

Route of Exposure

Symptoms

First Aid

Inhalation Headache. Nausea. Fresh air rest. Refer for medical attention.
Skin Redness. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. First rinse with plenty of water for several minutes (remove contact lenses if easily possible) then take to a doctor.
Ingestion Abdominal pain. Nausea. Unconsciousness. Vomiting. Weakness. Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention.
Notes for ICSC Information
MCPA is a chlorophenoxy-herbicide which as a group has been classified as possibly carcinogenic to humans. Depending on the degree of exposure periodic medical examination is indicated. Carrier solvents used in commercial formulations may change physical and toxicological properties.
 

Toxicity Information for MCPA

  Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

Summary Toxicity Information

PAN Bad Actor
Chemical
1
Acute
Toxicity
2
Carcinogen Cholinesterase
Inhibitor
Ground
Water Contaminant
Developmental or
Reproductive Toxin
Endocrine
Disruptor
Possible No
 
Indicates high toxicity in the given toxicological category. Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Detailed Toxicity Information

Acute Toxicity 2
MCPA
WHO Acute Hazard
TRI Acute Hazard
Material Safety Data Sheets
Acute rating from U.S. EPA product label
U.S. NTP Acute Toxicity Studies
      View Studies
Cholinesterase Inhibitor
III, Slightly Hazardous
Not Listed
Not Available
Highly Toxic
No NTP Studies

No
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.
 
Cancer Information
MCPA
IARC Carcinogens
U.S. NTP Carcinogens
California Prop 65 Known Carcinogens
U.S. EPA Carcinogens
TRI Carcinogen
2B, Possible
Not Listed
Not Listed
Not Likely
Not Listed
 
Endocrine Disruption
MCPA
Illinois EPA list
Keith list
Colborn list
Benbrook list
Danish Inert list
EU list
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 
Reproductive and Developmental Toxicity
MCPA
CA Prop 65 Developmental Toxin
U.S. TRI Developmental Toxin
CA Prop 65 Female Reproductive Toxin
CA Prop 65 Male Reproductive Toxin
U.S. TRI Reproductive Toxin
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 
Chemicals of Special Concern
MCPA
PAN Bad Actors
PAN Dirty Dozen list
Yes
Not Listed
 

Water Pollution Potential and Criteria for MCPA

Water Pollution Potential

PAN Ground Water Contaminant Rating Insufficient Data
 
Physical Property Data Related to Water Contamination Potential
Water Solubility (Avg, mg/L)
Adsorption Coefficient (Koc)
Hydrolysis Half-life (Avg, Days)
Aerobic Soil Half-life (Avg, Days)
Anaerobic Soil Half-life (Avg, Days)
29,390
74.0
-
15.0
-
 
 

Water Standards and Criteria

U.S. National Drinking Water Standards and Health Criteria
g/L unless noted  
Maximum Contaminant Level (MCL) 0  
Maximum Contaminant Level Goal (MCLG)  
One Day Exposure Health Advisory Level 100.0  
Ten Day Exposure Health Advisory Level 100.0  
Lifetime Exposure Health Advisory Level 30.0  
Reference Dose 4.00 (g/kg/day)  
U.S. Drinking Water Equivalent Level 140.0  
Concentration with Lifetime Cancer Risk of 1 in 10,000  
WHO Water Quality Criteria
Concentration (μg/l unless otherwise noted) 2.0
Canadian Water Quality Guidelines for the Protection of Agricultural Water Uses
g/L unless noted  
Irrigation Water Guidelines .025
Livestock Water Guidelines 25
 

Regulatory Information for MCPA

International Regulatory Status

 
UNEP Persistent Organic Pollutant (POP)
UNEP Prior Informed Consent Chemical (PIC)
WHO Obsolete Pesticide
Not Listed
Not Listed
Not Listed
 

U.S. and California Regulatory Status

U.S. EPA Registered
U.S. EPA Hazardous Air Pollutant
U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered
CA Groundwater Contaminant
CA Toxic Air Contaminant
No
Not Listed
No

No
Not Listed
In Evaluation
 

Maximum Tolerance and Residue Levels

Codex Alimentarius
   (UN FAO Maximum Residue Limits)
U.S. Maximum Tolerance Levels
European Union Maximum Residue Levels
Go to web site

Go to web site

Go to web site
 

Ecotoxicity for MCPA

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.

Aquatic Ecotoxicity

All Toxic Effects for Organism Group
Organism Group Effects Noted
Amphibians Hormone(s), Mortality, Reproduction
AquaticPlants Growth, Population
Crustaceans Behavior, Mortality
Fish Development, Enzyme(s), Intoxication, Morphology, Mortality, No Effect Coded
Insects Mortality
Molluscs Development, Growth, Intoxication, Mortality, Reproduction
Phytoplankton Cell(s), Growth, Physiology, Population
Zooplankton Intoxication, Morphology, Mortality, Physiology, Population
~ Un-Assigned Population
View All Aquatic Ecotoxicity Studies and References
 
Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
Amphibians Slightly Toxic
Crustaceans Not Acutely Toxic Not Acutely Toxic
Fish Slightly Toxic Not Acutely Toxic to High Toxicity
Insects Not Acutely Toxic Not Acutely Toxic
Molluscs Slightly Toxic Slight Toxicity
Zooplankton Slightly Toxic Slight Toxicity
View All Acute Summaries
 

Terrestrial Ecotoxicity

Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
HoneybeesSlightly ToxicSlightly Toxic
Note: Population-level effects on honeybees may occur even if a pesticide has low acute toxicity. For example, certain pesticides interfere with honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.
Honeybee Chronic Toxicity
Organism Group Chronic Toxicity  
Honeybees  

Related Chemicals for MCPA

CAS Number Relation Reason Chemical Name Chem Detail Symptoms California Use Chem Use Type U.S. EPA Reg PAN Bad Actor
94-74-6 Parent P MCPA View View View Herbicide No Yes
Related 5a 4-chloro-2-methylphenol View View View Breakdown product No Not Listed
401622-26-2 Related 5a Benzoic acid, 2-(carboxymethoxy)-4-chloro- View View View Breakdown product No Not Listed
Related 1 Hydroxy-MCPA View View View Plant Growth Regulator No Not Listed
25319-90-8 Related 1 MCPA thioethyl View View View Herbicide No Not Listed
29450-45-1 Related 1 MCPA, 2-ethyl hexyl ester View View View Herbicide Yes Not Listed
Related 1 MCPA, alkanolamine salt View View View Herbicide No Not Listed
19480-43-4 Related 1 MCPA, butoxyethanol ester View View View Herbicide No Not Listed
1713-12-8 Related 1 MCPA, butyl ester View View View Herbicide No Not Listed
20405-19-0 Related 1 MCPA, diethanolamine salt View View View Herbicide No Not Listed
42459-70-1 Related 1 MCPA, diisopropanolamine salt View View View Herbicide No Not Listed
2039-46-5 Related 1 MCPA, dimethylamine salt View View View Herbicide Yes Not Listed
Related 1 MCPA, ester View View View Herbicide No Not Listed
6365-62-4 Related 1 MCPA, ethanolamine salt View View View Herbicide No Not Listed
1713-11-7 Related 1 MCPA, isobutyl ester View View View Herbicide No Not Listed
26544-20-7 Related 1 MCPA, isooctyl ester View View View Herbicide Yes Not Listed
42459-69-8 Related 1 MCPA, isopropanolamine salt View View View Herbicide No Not Listed
2698-40-0 Related 1 MCPA, isopropyl ester View View View Herbicide No Not Listed
Related 1 MCPA, mixed amine salt View View View Herbicide No Not Listed
5221-16-9 Related 1 MCPA, potassium salt View View View Herbicide No Not Listed
3653-48-3 Related 1 MCPA, sodium salt View View View Herbicide No Yes
42459-68-7 Related 1 MCPA, triethanolamine salt View View View Herbicide No Not Listed
42459-71-2 Related 1 MCPA, triisopropanolamine salt View View View Herbicide No Not Listed
 
Working with the Information on this Page

Click on underlined terms for definitions or go to the Pesticide Tutorial overview page.

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* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

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