PAN Pesticides Database - Chemicals

Toluene - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Note: See Working with the Information on this Page section below for important notes about this data.

This website and underlying databases are maintained and updated by Pesticide Action Network North America (PAN). The project is made possible by our Sponsors and by PAN general funds. We need your support to maintain and improve this system. Please support the database and website — donate to PANNA.

Identifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of all products containing this chemical and a list of the top crops this pesticide is used on in California.
Signs and symptoms of poisoning, first aid, and links to treatment information for this chemical.
Link to information on toxicity to humans, including carcinogenicity, reproductive and developmental toxicity, neurotoxicity, and acute toxicity.
Links to world-wide registration status as well as regulatory information for the U.S. and California.
Water quality standards and physical properties affecting water contamination potential.
Toxicity to aquatic organisms.
List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.
 

Chemical Identification and Use for Toluene

Basic Identification Information About This Chemical
Chemical Name: Toluene
CAS Number: 108-88-3
U.S. EPA PC Code: 080601
080601
CA DPR Chem Code: 1281
Molecular Weight: 92.14
Use Type: Fuel or fuel additive , Industrial chemical , Paints, coatings, resins , Solvent
Chem Class: Petroleum derivative-Aromatic
View Related Chemicals
 
Additional Resources About This Chemical Class and Use Type
 
Other Names for this Chemical
About Chemical Synonyms
01281 (CA DPR Chem Code Text ) , 080601 [US EPA PC Code, Text ] , 108-88-3 (CAS number) , 108883 , 108883 (CAS number without hyphens) , 1281 (CA DPR Chem Code) ) , 80601 [US EPA PC Code, Numeric ] , Benzene, methyl- , Methyl benzene , Methylbenzene , Toluene , Toluene (SEE COMMENTS)
 
Products Containing This Chemical
Current and historic U.S. registered products
View U.S. Products All Products Currently Registered Products
 

Signs and Symptoms of Toluene Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.

Toluene is a Petroleum-derived compound.

Report a Poisoning

Symptoms of Poisoning with Petroleum-derived Compounds
Find Products Containing this Chemical

Rapid respiration, cyanosis, tachycardia, and low-grade fever usually indicate frank hydrocarbon pneumonitis.

Source for Group Symptoms: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 18.

Treatment for Petroleum-derived Poisoning

See: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 18, page 194.

 
Symptoms of Toluene Exposure from the International Chemical Safety Cards (ICSC)

Report a Poisoning

View full ICSC Cards: English   Español   Française   Chinese   Dutch   Finnish   German   Hungarian   Japanese   Swahili   Thai   Urdu  
NOTE! STRICT HYGIENE! AVOID EXPOSURE OF (PREGNANT) WOMEN!

Route of Exposure

Symptoms

First Aid

Inhalation Cough. Dizziness. Drowsiness. Headache. Nausea. Sore throat. Unconsciousness. Fresh air rest. Refer for medical attention.
Skin Dry skin. Redness. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
Eyes Redness. Pain. First rinse with plenty of water for several minutes (remove contact lenses if easily possible) then take to a doctor.
Ingestion Abdominal pain. Burning sensation. (Further see Inhalation). Rinse mouth. Do NOT induce vomiting. Refer for medical attention.
Notes for ICSC Information
Use of alcoholic beverages enhances the harmful effect. Depending on the degree of exposure periodic medical examination is indicated.
 

Toxicity Information for Toluene

  Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

Summary Toxicity Information

PAN Bad Actor
Chemical
1
Acute
Toxicity
2
Carcinogen Cholinesterase
Inhibitor
Ground
Water Contaminant
Developmental or
Reproductive Toxin
Endocrine
Disruptor
Unclassifiable No
 
Indicates high toxicity in the given toxicological category. Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Detailed Toxicity Information

This Chemical
Parent Chemical 
Acute Toxicity 2
Toluene Benzene
WHO Acute Hazard
TRI Acute Hazard
Material Safety Data Sheets
Acute rating from U.S. EPA product label
U.S. NTP Acute Toxicity Studies
      View Studies
Cholinesterase Inhibitor
Not Listed
Not Listed
Not Available
No Consensus Value
No NTP Studies

No
Not Listed
Not Listed
Not Available
No Consensus Value
No NTP Studies

No
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.
 
Cancer Information
Toluene Benzene
IARC Carcinogens
U.S. NTP Carcinogens
California Prop 65 Known Carcinogens
U.S. EPA Carcinogens
TRI Carcinogen
3, Unclassifiable
Not Listed
Not Listed
D, Unclassifiable, inadequate data
Not Listed
1, Known
Known
Yes
A, Known
Not Listed
 
Endocrine Disruption
Toluene Benzene
Illinois EPA list
Keith list
Colborn list
Benbrook list
Danish Inert list
EU list
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 
Reproductive and Developmental Toxicity
Toluene Benzene
CA Prop 65 Developmental Toxin
U.S. TRI Developmental Toxin
CA Prop 65 Female Reproductive Toxin
CA Prop 65 Male Reproductive Toxin
U.S. TRI Reproductive Toxin
Yes
Not Listed
Yes
Not Listed
Not Listed
Yes
Not Listed
Not Listed
Yes
Not Listed
 
Chemicals of Special Concern
Toluene Benzene
PAN Bad Actors
PAN Dirty Dozen list
Yes
Not Listed
Yes
Not Listed
 

Water Pollution Potential and Criteria for Toluene

Water Pollution Potential

This Chemical
Parent Chemical
  Toluene Benzene
PAN Ground Water Contaminant Rating Insufficient Data Insufficient Data
 
Physical Property Data Related to Water Contamination Potential
Water Solubility (Avg, mg/L)
Adsorption Coefficient (Koc)
Hydrolysis Half-life (Avg, Days)
Aerobic Soil Half-life (Avg, Days)
Anaerobic Soil Half-life (Avg, Days)
-
-
-
-
-
 
 

Water Standards and Criteria

This Chemical
Parent Chemical
U.S. National Drinking Water Standards and Health Criteria
g/L unless noted  
  Toluene Benzene
Maximum Contaminant Level (MCL) 1,000  
Maximum Contaminant Level Goal (MCLG) 1,000  
One Day Exposure Health Advisory Level 20,000  
Ten Day Exposure Health Advisory Level 2,000  
Lifetime Exposure Health Advisory Level  
Reference Dose 80.0 (g/kg/day)  
U.S. Drinking Water Equivalent Level 3,000  
Concentration with Lifetime Cancer Risk of 1 in 10,000  
Canada Drinking Water Standards and Criteria
g/L unless noted  
Maximum Acceptable Concentration (MAC)
Interim Maximum Acceptable Concentration (IMAC)
Aesthetic Objectives ≤24
U.S. National Water Quality Criteria
g/L unless noted  
  Toluene Benzene
Fresh Water Quality Criteria Continuous Exposure 0  
Fresh Water Quality Criteria Maximum Peak  
Salt Water Quality Criteria Continuous Exposure
Salt Water Quality Criteria Max
Human Consumption of Organisms from Water Source 15,000
Human Consumption of Water and Organisms from Water Source 1,300 Notes: z
Taste and Odor Criteria
WHO Water Quality Criteria
Concentration (μg/l unless otherwise noted) 700.0
Notes Notes: C
Canadian Water Quality Guidelines for the Protection of Aquatic Life
g/L unless noted  
Fresh Water Guidelines 2.0 Notes: c,j,k
Salt Water Guidelines 215 Notes: c,k
Canadian Water Quality Guidelines for the Protection of Agricultural Water Uses
g/L unless noted  
Irrigation Water Guidelines
Livestock Water Guidelines 24
 

Regulatory Information for Toluene

International Regulatory Status

This Chemical
Parent Chemical 
 
UNEP Persistent Organic Pollutant (POP)
UNEP Prior Informed Consent Chemical (PIC)
WHO Obsolete Pesticide
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 

U.S. and California Regulatory Status

U.S. EPA Registered
U.S. EPA Hazardous Air Pollutant
U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered
CA Groundwater Contaminant
CA Toxic Air Contaminant
No
Yes
No

No
Not Listed
HAPTAC, Industrial chemical
No
Yes
No

No
Not Listed
HAPTAC, Industrial chemical
 

Maximum Tolerance and Residue Levels

Codex Alimentarius
   (UN FAO Maximum Residue Limits)
U.S. Maximum Tolerance Levels
European Union Maximum Residue Levels
Go to web site

Go to web site

Go to web site
 

Ecotoxicity for Toluene

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.

Aquatic Ecotoxicity

All Toxic Effects for Organism Group
Organism Group Effects Noted
Amphibians Growth, Mortality
Annelida Behavior
Cnidaria Behavior
Crustaceans Accumulation, Behavior, Mortality
Fish Accumulation, Avoidance, Behavior, Biochemistry, Enzyme(s), Growth, Histology, Mortality, Physiology
Insects Behavior, Intoxication, Mortality
MarineBenthicCommunity Reproduction
Molluscs Development, Feeding Behavior, Mortality
Phytoplankton Accumulation, Biochemistry, Growth, Physiology, Population
Zooplankton Accumulation, Avoidance, Behavior, Development, Enzyme(s), Intoxication, Mortality, Population, Reproduction
View All Aquatic Ecotoxicity Studies and References
 
Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
Amphibians Not Acutely Toxic Not Acutely Toxic
Crustaceans Slightly Toxic Slight Toxicity
Fish Slightly Toxic Not Acutely Toxic to Moderate Toxicity
Insects Not Acutely Toxic Not Acutely Toxic to Slightly Toxic
Molluscs Not Acutely Toxic Not Acutely Toxic to Slightly Toxic
Zooplankton Not Acutely Toxic Not Acutely Toxic to Moderate Toxicity
View All Acute Summaries
 

Terrestrial Ecotoxicity

Summary of Acute Toxicity for Organism Group

Sorry, no honeybee acute toxicity data available for this chemical. Try related chemicals.

Note: Population-level effects on honeybees may occur even if a pesticide has low acute toxicity. For example, certain pesticides interfere with honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.
Honeybee Chronic Toxicity
Organism Group Chronic Toxicity  
Honeybees  

Related Chemicals for Toluene

CAS Number Relation Reason Chemical Name Chem Detail Symptoms California Use Chem Use Type U.S. EPA Reg PAN Bad Actor
71-43-2 Parent P Benzene View View View Solvent, Fuel or fuel additive, Chemical intermediate, Impurity No Yes
68919-17-5, 67674-15-1, 68516-20-1 Related 15 Alkylated aromatic petroleum oil View View View Insecticide, Adjuvant No Yes
Related 15 Aromatic 100 View View View Insecticide, Solvent No Yes
Related 15 Aromatic 150 View View View Insecticide, Solvent No Yes
108-38-3, 106-42-3 Related 2 m- and p-Xylene View View View Solvent No Not Listed
64742-94-5 Related 15 Naphtha, heavy aromatic View View View Insecticide, Solvent Yes Yes
95-47-6 Related 2 o-Xylene View View View Solvent No Not Listed
68477-31-6, 63231-51-6, 64743-95-6 Related 15 Petroleum distillates, aromatic View View View Solvent, Herbicide, Insecticide Yes Yes
65996-79-4 Related 15 Solvent naphtha (coal),150-200 deg. C View View View Solvent No Not Listed
68920-06-9, 64742-95-6 Related 15 Solvent naphtha (petroleum), light aromatic View View View Solvent, Insecticide No Yes
108-88-3 Related 2 Toluene View View View Solvent No Yes
1330-20-7 Related 2 Xylene View View View Solvent, Microbiocide No Not Listed
 
Working with the Information on this Page

Click on underlined terms for definitions or go to the Pesticide Tutorial overview page.

Any underlined term with a book icon has additional information.

* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

To print this page, choose Print. To export this data, choose Save As 'HTML Source' and open it in Excel or equivalent program.